Keeper can get money very quickly through Wooden Nickel and infinitely playing Blood Banks for spare nickels/dimes, so shops are essentially free for finding survival items or items for breaking the game. But Succubus, Rotten Baby and Guppy Items can be very helpful. Taking a Devil Deal ususally won't provide much benefit since many deals don't carry a Keeper run and the risk is compounded by no Angel deals. Orbitals are essential playing defensively, or even offensively. Flight also helps mitigate Keeper's slow speed, and enables the strategy of playing defensively like you would do the Lost. Playing defensively is the best way to play Keeper, don't overextend Devil Deals, Curse Rooms or even normal rooms can since they can potentially kill Keeper very fast. Keeper can get very strong when you find more and more damage ups where flies appear often from health pickups. It's better to look for a way to reroll items/the entire run where most items you pick up are going to be functionally useless, such as HP up.įocusing on DPS items and orbitals will make Keeper runs easier, just get lucky. You can't take Devil Deals except uncommon circumstances where you have HP ups lying around or a Strength Card, so Angel Deals are much better. Keeper is a generally weaker character options-wise.

Originally posted by kitten exterminator:

Binding of isaac keeper